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On one hand, 1,25(OH)D can attenuate VDR ubiquitination and delay its degradation (17)

377380 An elevated level of primary BA (cholic acid) was identified in the plasma of PD patients

In addition, some drugs require metabolism to generate an active metabolite or functional therapeutic agent (see Table 1)
For the purpose of these studies we employed a C57Bl/6xCBA F1 hybrid cross (F1) mouse model since the age-dependent oocyte deterioration previously documented in this strain, mirrors that which occurs in humans
