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According to multiple studies, sperm analysis of all animals that received busulfan indicated that busulfan can significantly reduce sperm concentration, motility, viability, normal morphology, and DNA integrity (39, 4143)

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Data were excluded if the mice did not conduct a minimum of predefined number of entries according to the protocol

General guidelines recommend 150300 minutes of moderate-intensity activity (or 75150 minutes of vigorous-intensity activity) per week, plus strength training at least twice a week