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Hepatic overexpression of PPAR attenuates MASH progression by suppressing ferroptosis and fibrogenesis To assess the in vivo role of PPAR in modulating MASH progression, we generated a liver-specific overexpression model using AAV8 carrying the hepatocyte-specific TBG promoter (AAV8-TBG-PPAR), with AAV8-TBG-GFP as a control (Fig

A review article on exercise intolerance in long COVID: Unmasking the causes and optimizing treatment strategies

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Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW