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Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer

Once the superoxide and hydrogen peroxide are produced, they undergo different cellular reactions and then transform into highly powerful hydroxyl radical free radicals via the Fenton and HaberWeiss reaction (106)

Antimycin A, a complex III inhibitor, significantly reduced the rate of cytochrome c reduction

Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity

Additionally, it has been shown that decreased glutathione, and the consequent increase in ROS levels, results in a decline of calcium absorption, hindering the effective mineralization of the skeleton [13]

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