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J.et al

Melatonin is a hormone produced naturally by the body that helps regulate the sleep-wake cycle
The RNA-binding protein SND1 binds to the 3UTR of HSPA5, destabilizing HSPA5 mRNA, thereby inhibiting GPX4 and promoting ferroptosis in osteoarthritis

Interventions that increase NAD+, including supplementing with NAD+ directly, may slow the aging process
Immune-related adverse events in patients with pre-existing autoimmune rheumatologic disease on immune checkpoint inhibitor therapy
ILA is derived from commensal bacterium, such as Bifidobacterium , and plays important roles in regulating inflammation 49
