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older, non-selective agents are available for different routes of administration [i.e., oral (PO), intramuscular (IM), and intravenous (IV)] and continue to be investigated actively (Henter et al., 2017

In studies treating patients with Rett syndrome, doses of 50 mg/kg/day or 100 mg/kg/day were used in three divided doses [84,85,86]

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Biochem Biophys Res Commun 419: 573577, 2012

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These usually resolve within 12 weeks