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13 The occurrence of PHPV in the cat is very rare and poorly documented
SLC6A4 increase the uptake of glutamine and GLS1 converts glutamine to glutamate and ultimately forms some intermediates of the TCA cycle [138]
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Concerning metabolism, it is important to analyze the interactions between compounds and cytochrome P450, particularly their roles as inhibitors or substrates of the CYP2D6 and CYP3A4 isoenzymes, which are essential for drug metabolism
