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demonstrated in enteric glial cell models that PS-NPs accelerate the aggregation of mutant A53T -synuclein, disrupt mitochondrial membrane integrity, and impair lysosomal function, collectively exacerbating dysregulation of the mitochondrial-lysosomal axis 41

doi: 10.29063/ajrh2022/v26i8.9 2 Stener-VictorinETeedeHNormanRJLegroRGoodarziMODokrasAet al

Zhuo S, He G, Chen T, Li X, Liang Y, Wu W, et al

Unfortunately, BSO is no longer being clinically applied due to its short in vivo half-life and its disappointing capacity to lower glutathione levels in tumour tissue [41]

Adenosine triphosphate inhibits melatonin synthesis in the rat pineal gland

Shortly, 50 l of capture bead mix was added to each well of the plate