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Becoming older will unavoidably deplete glutathione

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By phosphorylating 4E-BP1, mTORC1 forces it to release another protein called eIF4E, effectively removing the brakes on cellular translation and allowing the cell's ribosomes to begin assembling new muscle tissue

We also thank the Boston Childrens Hospital Hematology/Oncology and Harvard Stem Cell Institute Flow Cytometry Research Laboratory for their services, as well as the Genomic Perturbation Platform at the Broad Institute