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however, these medications often turn the acute inflammation and rapid progression of renal disease into chronic inflammation and slow, but do not stop, the still inevitable progression of end-stage renal disease

When your therapy already has inherent biological variability in its starting materials, your reagents shouldn't be adding to it

10.1038/cddis.2013.158 Cell Death Dis

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Regular serum B12 monitoring is not routinely necessary once stable on replacement therapy, as levels become artificially elevated and unreliable

[Accessed April 2026] Pharmacy Board of Australia, Codes, guidelines, and FAQ on compounding of medicines