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The mTBI model was shown to have an intermediate level of neuroinflammatory state (Michalovicz et al., 2023)

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10.3390/biomedicines9020169 Biomedicines 21 CatanzaroM

In the prone position, the skin overlying the frontal region of the skull was incised, and the soft tissues dissected to expose the skull

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This enzymatic stimulation appears tissue-specific, as Epithalon selectively protected aged human pinealocytes from degenerative changes while promoting functional restoration of the gland's secretory capacity