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There is evidence here

It is well recognized that the toxicity of arsenicals largely depends on the oxidoreduction states (trivalent or pentavalent) and methylation levels (monomethyl, dimethyl, and trimethyl) that are present during the process of metabolism in mammals

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Supports healthy methylation pathways

Liquid chromatography tandem mass spectrometry highlights potential serum biomarkers for early diagnosis of rheumatoid arthritis.