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doi: 10.1194/jlr.M800042-JLR200

Note: Vitamin C cannot be added as an option to the Glutathione IV

2017;11(Suppl 2):S631S635

Hydroperoxides (ROOH) Hydroperoxides are unstable compounds formed via lipid (LOOH), protein (POOH), and DNA oxidation, originating primarily from three hepatic sources: (1) electron leakage from the mitochondrial electron transport chain (particularly Complex I/III), (2) ROS-generating activity of CYP2E1, and (3) the NOX enzyme family (predominantly NOX4)

2021;8 doi: 10.1002/advs.202101090

PMID: 42284407 Nat Struct Mol Biol RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth
