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As previously described, the RAAS becomes activated during DKD

PND tends to occur in elderly patients and is mainly characterized by diminished attention, memory, and verbal thinking skills

Donato, J

Acknowledgments The author thanks the Faculty of Medicine, Chiang Mai University, for academic support and access to institutional resources

Assuming the above, the researcher may administer DSIP via nasal spray as follows: DSIP Dosage: A total daily dose of 300mcg, with 150mcg administered in each nostril in three sprays of 50mcg each, may be applied