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Int J Nutrol (2023) 16
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Discovery of a potent, selective, and orally available MTHFD2 inhibitor (DS18561882) with in vivo antitumor activity

Well-studied S-palmitoylated proteins such as calnexin (CALX), Thioredoxin-related transmembrane protein 1 (TMX1), Synaptosomal-associated protein 23 (SNAP23), Ras-related protein (RRAS), Phosphatidylinositol 4-kinase II (P4K2A), transferrin receptor (TFR1), G-proteins (GNAI2, GNAI3), Ras related proteins were identified in multiple palmitoyl-proteome screens (at least in 10 out of 19) in at least four different species (Table 1, Supplementary table S3) 6,50,6267
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