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Although Wnt/-catenin signalling is an attractive target evaluated by clinical trials, there is a risk of off-target effects, such as the following: side effects such as diarrhoea, fatigue, nausea dysgeusia, and vomiting 315 kidney injury

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Kazakova TB, Barabanova SV, Khavinson VKh, Glushikhina MS, Parkhomenko EP, Malinin VV, et al

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It aims to dissect the molecular pathways, evaluate the animal model data, and critically assess the state of human research to equip clinicians with a balanced and actionable perspective