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Third, rigorous preclinical and clinical studies are essential to validate the safety, efficacy, and optimal dosing of these compounds in HCC patients

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The key findings of the 36 studies was the mechanism of action is angiogenesis, so blood flow, creating new blood flow to an area, collagen synthesis, anti-inflammatory effects, and neuroprotection

Zhu Y, Hu Y, Huang T, Zhang Y, Li Z, Luo C, et al

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Hence, while animal models serve as powerful research platforms for interrogating virushost relationships, these important factors will influence generalization, and require caution when making clinical predictions 165