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Noshita, N., Lewen, A., Sugawara, T

NLRP3 inflammasome activation triggers gasdermin D-independent inflammation

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To demonstrate that the reversible covalent warheads increase the cellular residence time as expected, we carried out cell-based wash-out experiments using the physiologically relevant AP-1 promoter-based reporter assay as well as the more direct NanoBRET target engagement assay

Store reconstituted preparations away from light and extreme temperature variations

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