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There are indications that silymarin may have a mild oestrogen-like effect

B vitamin acquisition by gut commensal bacteria
Discovery of a potent and orally efficacious TGR5 receptor agonist

Zhang, K., Coyne, A

Additionally, in one of the earliest studies done on ipamorelin (published in 1999), researchers found that ipamorelin administration actually appeared to increase the length of long bones in rats particularly the tibia, a leg bone [6]

Shen and Pappano, 1997)
