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Computational analyses identified 5-hydroxymorin as a promising lead with strong binding affinity and favorable drug-like features, offering an efficient route for developing targeted liver therapies (73)

Ekstrm K, Pulkkinen MA, Carlsson-Skwirut C, Brorsson AL, Ma Z, Frystyk J, Bang P

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Delrobaei M, Memar S, Pieterman M, Stratton TW, McIsaac K, Jog M

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Additional studies indicate that HOTAIR overexpression in PD facilitates SSTR1 gene methylation, worsening motor function and dopaminergic neuron survival (191)