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doi: 10.1016/j.jaad.2017.05.033

ROS-producing enzymes involved in the increased vascular oxidative stress observed during hypertension include the NADPH oxidase, xanthine oxidase, the mitochondrial respiratory chain and an uncoupled endothelial NO synthase

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Some findings reveal that the absence of HIF-1 impairs the ability of dendritic cells to induce regulatory Treg, resulting in exacerbated intestinal inflammation in mice (80)

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