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We thank Ashlee Hoffman (CWRU) for proofreading the manuscript

While sustained firing of action potentials or longer lasting depolarization are keys to neuronal BDNF secretion, the subsequent signaling cascades and the molecular machinery triggering and regulating BDNF vesicle exocytosis have just begun to be elucidated

10.1016/j.cell.2013.12.016 Cell 16 DonnellanC.WerringD

Customized dietary modifications often involve implementing special diets such as gluten-free and casein-free (GFCF) diets

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The ProTox-II server was used to determine predicted acute oral toxicity of the phytochemical compounds in rodents based upon 2D structure similarities with 38,000 compounds (provided by the software) and their associated LD50 values