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Somasundaram S, Rafi S, Hayllar J et al (1997) Mitochondrial damage: a possible mechanism of the topical phase of NSAID induced injury to the rat intestine

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In Phase 2 trials published in the *New England Journal of Medicine* (2023), participants lost an average of 17.5% of body weight at the highest dose over 24 weeks outperforming tirzepatide and semaglutide in head-to-head data comparisons