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Clinical studies showed that post-colonoscopy CB supplementation can upregulate the expression of the buk gene (encoding butyrate kinase), enhance butyrate production, and accelerate homeostasis of the microbiota and colonic mucosal microenvironment (75)

Brewster, M

While 503B outsourcing facilities are subject to federal Current Good Manufacturing Practice (CGMP) regulations and must register with the FDA, traditional 503A compounders are exempt from CGMP regulations and are instead overseen primarily by state boards of pharmacy, potentially resulting in a patchwork of manufacturing regulation and oversight across states (Lisi, 2021

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The fat-loss, NAD+, and muscle findings people cite are all preclinical too

Nausea or upset stomach can be experienced by some people as mild digestive issues