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Therapy should be evaluated and lab work should be reviewed to see what the levels are, determine if the levels are low, determine if the levels are rising appropriately with therapy, and assure that this therapy is having an effect and is needed and useful

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doi: 10.2353/ajpath.2008.070597 105 GonzalezLZambranoALazaro-TruebaILopezEGonzalezJJMartin-PerezJet al