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Description
This approach sacrifices some systemic anabolic signaling but preserves receptor sensitivity longer than daily dosing by allowing 23 rest days per week where IGF-1 receptors are not actively stimulated

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The phenotype of the proband was less severe than other IGF1 mutation patients with normal birth size (3.0kg) but significant post-natal growth impairment (presenting height -4.0 SD), normal hearing, normal development except for attention deficit hyperactivity disorder and mildly reduced serum concentrations of IGF-I (-2.2 SD) with normal IGFBP-3 serum levels (-1.25 SD)

Die optimale Schlafdauer pro Tag liegt zwischen 7 und 9 Stunden

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Pasparakis M, Vandenabeele P

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