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It was effectively applied either immediately (prophylactically) after paracetamol challenge or (therapeutically) administered after a 3 h period had elapsed (note, the maximum depletion of hepatic glutathione occurred 3 h after acute paracetamol dosing (37))

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[11] To avoid this, always ensure that the final admixture is approximately isotonic, typically achieved by the drug or other diluents added to the bacteriostatic water, before injecting into the bloodstream

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If additional glycemic control is needed: Increase from 5 mg to 7.5 mg subcutaneously for 4 weeks and thereafter in 2.5 mg increments after at least 4 weeks on the current dose

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