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Guanidinoacetate (GAA) is a potent GABA(A) receptor GABA mimetic: implications for neurological disease pathology

Oxidative stress exaggerates disease condition by interfering with various signaling pathways like RCAN1, CREB/ERK, Nrf2, PP2A, NFB and PI3K/Akt

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For example, antibiotics such as gentamicin, the antifungal amphotericin B, corticosteroids including prednisone, antacids, and insulin may reduce magnesium levels in the body when combined