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The cost of treatment to eradicate established ADAs is very high, such as in the case of hemophilia (over $7,00,000/year/patient) [13]

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doi: 10.1002/j.1939-4640.2001.tb02579.x, 186

Raw kinetic data collected were processed by the manufacturers supplied data analysis software using a dual reference subtraction method where both the DMSO-only reference and the inactive protein reference were subtracted

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