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The cannabinoid antagonist SR141716A facilitates memory acquisition and consolidation in the mouse elevated T-maze

In this study, we choose the following immune cell marker genes as the label for each cell cluster and use the UMAP feature map and bubble map to show the expression of the marker genes 22 : Naive T (LEF1, CCR7), Effector memory CD8 + T (CD8A), Activated CD4 + T (IL7R), Circulating NKs (FCGR3A, TYROBP), Naive B cell (IGHD, TCL1A), Regulatory T cell (IL2RA), Memory B cell (AIM2, TNFRSF13B), NKs (GZMB, XCL1), Plasma cell (JCHAIN, MZB1), Monocyte (LYZ, S100A9), Proliferating CD4 + T (MKI67, TOP2A), Megakaryocyte (PPBP, PF4), DCs (PLD4, SOX4)

doi: 10.1007/s10753-023-01861-y, 146

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Therefore, although data from mice implicate Glo1 in increasing depression-like behavior, further experiments are required to resolve the discrepancy with human data

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