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Biochemistry 52 , 57605769 (2013)

Finally, a total of 5,575 participants were included in the present study

Quercetin synergistically enhances mitochondrial spare respiration, maintains neuronal mitochondrial function, and increases the expression of CREB target genes (PGC-1a), which promote neuronal survival and mitochondrial biogenesis in an OGD model (Nichols et al., 2015)

Although this competitive phenomenon has not yet been observed in the brain, it may be a significant reason for the poor efficacy and side effects of many therapeutic approaches, warranting further investigation

Recent advances in immunological research have led to the development of new treatments that can control symptoms, but not cure the disease

Consistent with the role of LILRB1 in cholesterol uptake [47], subsequent analysis of LILRB1 KD MM cells from the mice confirmed they contained lower levels of intracellular LDL-cholesterol than MM cells from the control mice [47]