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IGF-1-LR3 IGF-1-LR3 (Long Arg3 IGF-1) is a modified variant of Insulin-like Growth Factor-1 with a much longer half-life and significantly reduced binding to binding proteins

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They are mild by design, but like any injection, they can cause reactions

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Myeloperoxidase (MPO) converts it to HOCl, which efficiently chlorinates and destroys ingested microbes [145], while its reaction with NO forms ONOO , contributing to microbial killing through nitration [146, 147]