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Previous studies have indicated that metformin administration during pregnancy has shown limited impact on fetal growth and development in patients with PCOS but may result in increased head circumference in the offspring of overweight mothers (Landi et al., 2019

It has also been shown to have beneficial effects in patients with end-stage renal disease and alcoholic neuropathy

Spiders, as one of the largest groups of arthropods besides insects, are home to 50,708 known species worldwide [1], with a diverse range of symbiotic bacteria present in their bodies [2, 3]

Lee et al., 2005), PIP 2 also has the potential to enhance TRPV3 functionality and regulate TRPV5 inhibitory responses to Mg 2+ , highlighting the complexity and controversial activity of inositol phospholipid (Lee et al., 2005

212 At present, four subtypes (A 1 , A 2a , A 2b and A 3 ) of adenosine receptors have been cloned

Dupilumab combined with methylprednisolone and azathioprine demonstrated benefits in managing the progression of the disease and expediting the decrease in glucocorticoid dosage (218)