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FolTAC-mediated POI endocytosis into the lysosome Previous studies have shown that FR is constantly endocytosed upon binding with its physiological ligand, folic acid 30,31

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Hoefer IE

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Thank you to our sponsors AG1 (Athletic Greens): InsideTracker: Thesis: Supplements from Momentous For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Social Bonding: Child-Parent, Romantic, Friendship, Breakups (00:02:55) Sponsors (00:07:08) Social Bonding as a Biological Process (00:10:03) Social Isolation (00:13:32) Social Homeostasis & Neural Circuits for Social Drive (00:18:55) Brain Areas & (Neuro)Chemistry of Social Drive (00:22:48) What is Social Homeostasis & Dopamine (00:27:00) When We Lack Social Interactions: Short- Versus Long-Term (00:28:10) Introverts & Extroverts (00:31:00) Good Versus Bad Social Interactions & Hierarchies (00:33:54) Loneliness & Dorsal Raphe Nucleus & Social Hunger (00:37:33) Tools (00:38:05) Socializing & Food Appetite: Crossover Craving (00:42:45) Falling in Love (00:45:05) Tools for Social Bonds: Merging Physiologies