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Hirschsprung's Disease - Review of Clinical Features, Diagnosis and Treatment

In addition, it is possible that in spared brain regions, the aggregation process is assisted and controlled by cellular-specific quality control mechanisms in such a way that toxicity is maintained subthreshold, avoiding cell dysfunction and death

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doi: 10.1016/s0968-0004(96)80167-8 35 WrightNTCannonBRWilderPTMorganMTVarneyKMZimmerDBet al

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Compared to young MuSCs, fewer aged MuSCs are found in quiescence, due to either elevated activation or entering a pre-senescent state 5,6
