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Moving forward, efforts should focus on developing novel iron chelators with higher brain selectivity and improved safety profiles to achieve an optimal balance between therapeutic efficacy and risk management

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10.1016/j.freeradbiomed.2009.06.010 219 ParmentierM.DrostE.HiraniN

Quellen: Lau et al., dosisfindende Phase-II-Studie zu Cagrilintid, The Lancet (2021, n=706)

To quantify these traits across the genome, numerous techniques have been devised