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Copper is a critical trace element involved in numerous biological processes, including the formation of red blood cells, the function of the immune system, and the maintenance of connective tissues

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IGF-I/BP-3 administration preserves hepatic homeostasis after thermal injury which is associated with increases in no and hepatic NF-kappa B

References Htut TW, Thein KZ, Oo TH

In severe cases, deficiency may result in glossitis (inflammation of the tongue) or mouth ulcers

Less common but important risks include gallbladder disease, pancreatitis, and the boxed warning for medullary thyroid carcinoma based on rodent data