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These diseases exhibit pathological features including neurodegeneration, neuronal cell loss, excessive glial cell inflammation, and impaired bloodbrain barrier (BBB) function [4, 5] Despite the introduction of new drugs, treatment efficacy is significantly limited by the complex mechanisms of CNS disorders, drug tolerance, and inadequate drug targeting [6]
Huang X, Jia Z, Li X, Hu Z, Yu X, Xia J

PMID 11934214

An ultraviolet (UV) spectrophotometric method has been reported for the simultaneous estimation of EST and CZP in tablet formulations, which was simple, accurate, and precise [3]

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Why someone might choose fasting over continuous caloric restriction [19:00]