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We do broadly observe a shift from monocytes and macrophages that express pro-inflammatory markers to anti-inflammatory markers, but there are significant differences by age (Fig
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We further used flow cytometry to quantify CD45 + CD11c CD11b TCR + T cells at days 0 and 5 from dissociated TA muscles of young, old and geriatric mice (Fig

Understanding how CD38 enzymatic activity and adenosinergic metabolism evolve during therapy is essential for improving treatment efficacy

112 pmol/L ( n = 119), P 0.30 for tests of interaction)
