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lenta (SP5-62) and SP2-71.3 (or the entire SP2-71 pool) were present, which suggests that E

129 , identifies GFRAL as the receptor for GDF15, expressed by neurons in the area postrema and the nucleus tractus solitarius of the mouse brainstem, which mediates GDF15-dependent feeding responses to stress and disease conditions

Moreover, it is not known if S-5-HT mediated the effects of L-carnitine on fatigue, as it is possible that L-carnitine could have effects unrelated to S-5-HT that could reduce fatigue and in parallel promote increased synthesis of peripheral 5-HT

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On this basis, the oral administration of L-theanine (200 mg/kg BW) could repair the normal brain structure, downregulate the expression of inflammatory cytokines, so as to protect the brain from the oxidative lesion (42)
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