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Cadmium exposure can cause increased levels of ROS [171], epigenetic changes including DNA methylation and chromatin remodeling [172] and activation of ER and downstream pathways (Figure 4) [173]

6l, m), suggesting that Nrf2 activation could be a promising therapeutic pathway for DENV-2 treatment

Wilson DF, Mokashi A, Chugh D: The primary oxygen sensor of the cat carotid body is cytochrome c3 of the mitochondrial respiratory chain

doi: 10.1146/annurev-bioeng-062117-121224 16 MylvaganamSFreemanSAGrinsteinS

doi: 10.1093/eurjhf/hfs066
