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In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application

IM injection requires systemic circulation to redistribute the peptide back to adipose depots

In fact, cultured adipocytes secrete more IGF-2 than IGF-1, and predominantly IGFBP-4

Ann Nutr Metab 2012;60:27292

Other peptides are prescribed legally as compounded medications through specialized clinics to support weight loss

FLASH: Fast length adjustment of short reads to improve genome assemblies (in Eng)