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When human SGECs are cultured with IL-6 for 24 to 72 hours, a downregulation of epithelial markers, an upregulation of mesenchymal markers, and a clear morphological change to a mesenchymal phenotype can be observed (56)

Its chronic inflammation beneath the surface, broken capillaries, a compromised skin barrier, and an immune system thats constantly in a low-grade reactive state

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Its one of the most important molecules in the body because it protects cells from the damaging effects of toxins and oxidative stress

doi: 10.3389/fimmu.2018.02763 259 SchornCJankoCLatzkoMChaurioRSchettGHerrmannM