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[DOI] [PMC free article] [PubMed] [Google Scholar] 270.Mutlu E.A., Engen P.A., Soberanes S., Urich D., Forsyth C.B., Nigdelioglu R., Chiarella S.E., Radigan K.A., Gonzalez A., Jakate S., et al

You can observe lethargy, weak muscles, tiredness or thinning of coat in dogs

As a dual amylin and calcitonin receptor agonist (DACRA), it binds both receptors to suppress appetite and regulate glucose

Gozes group has found that ADNP mutations affect MT dynamics and inhibit its interactions with Tau [348, 349], producing a tauopathy-like phenotype manifested in increased GSK-3 activity, Tau hyper-phosphorylation, and cognitive deficiency [293]

Ferroptosis is an effective way to kill tumor cells by radiotherapy, and radiotherapy-resistant tumor cells are often accompanied by reduced levels of ferroptosis

On the other hand, some drawbacks that brain organoid protocols collectively share are limited oxygen and nutrient diffusion with consequent necrosis, cellular immaturity, and the absence of certain cell types found in the brain, such as microglia and vascular cells ( Another important limitation of current protocols includes the lack of vasculature in the generated brain organoids that limits the supply of nutrients and oxygen to the organoid core