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A 2.5 mg dose now equals 1.0 mL

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis

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Collectively, our data highlight membrane lipid interaction as a crucial determinant of -SNAP functional efficiency in membrane fusion events and reconcile previous discrepancies: the M105I mutation does not reduce -SNAPs ability to disassemble soluble SNARE complexes in vitro (without lipids) 14 but undermines -SNAP functions in cellular contexts (with membrane lipids) 25

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