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Laboratory data including serum creatinine, Blood Urea Nitrogen (BUN), hemoglobin, platelet and white blood cell (WBC) counts, albumin, sodium and potassium were also collected daily during 5 days of study period

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This inflammatory process is characterized by the activation of resident glial cells, the release of proinflammatory cytokines and chemokines, and the recruitment and infiltration of peripheral cells into the CNS as a consequence of the breakdown of the blood-brain barrier (Kelly et al., 2020)

Moreover, after a prolonged fast, a plasma glucose response 1.4 mmol to intravenous glucagon and a plasma -hydroxybutyrate level 2.7 mmol indicate hyperinsulinemia induced by insulinoma [77]

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