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Together, these findings demonstrate that GSNO is a potent vasodilator in both conductance (aortic) and resistance (coronary) vessels

[DOI] [PubMed] [Google Scholar] 72.Cook NL, Van Den Heuvel C, Vink R

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Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]