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Among them, the best known ROS in human cells include superoxide anion (O 2 - ), which is the precursor of most other ROS, hydroxyl radical ( OH), peroxyl radical (ROO ), hydroperoxyl radical ( HO 2 ), and hydrogen peroxide (H 2 O 2 ), although the last one is not technically a free radical because it does not have unpaired electrons, but it represents a source of them [25] (Fig

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Most recently, a randomized, double-blind, placebo-controlled trial in 81 children (8-14 years) residing in the UK found that use of a daily multivitamin/mineral supplement, containing most vitamins as well as iron, copper, zinc, calcium, and magnesium, was associated with an increase in accuracy on one attention task (Arrows Flankers test) throughout the 12-week study (106)