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Consequently, mechanisms that modulate the availability of L-cysteine are likely to impact both the H 2 S production pathway and GSH biosynthesis, as evidenced by metabolomics and transcriptomics studies conducted in diverse models of mitochondrial dysfunction

The risk estimates from the studies described above may not be generalizable to all patients receiving opioid analgesics, such as those with exposures shorter or longer than the duration evaluated in the studies

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Oral tablets have a lower risk of side effects and are FDA-approved for treating certain serious illnesses.

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