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In the diabetes model, the high-sugar environment induces excessive expression of GCN5L, resulting in abnormal acetylation at the K246 site of the ATP synthase subunit of complex V, thereby reducing the efficiency of proton gradient-driven ATP synthesis (Pan, 2022)

KD has also been shown to cause changes in amino acid metabolism, in particular, a reduction in levels of -aminoadipic acid, a key biomarker of cancer (222)

See additional terms and conditions for Chegg Study or Chegg Study Pack on Chegg.com Show transcribed image text Question: Shown below is the structure of Glutathione-S-Transferase with different subunits drawn in different colours